Volume : 7, Issue : 1, January - 2018

CLINICOPATHOLOGICAL STUDY OF MENINGIOMA: 10 YEAR EXPERIENCE FROM A TERTIARY CARE HOSPITAL

Vipra Malik, Rps Punia, Arvind Malhotra, Vipin Gupta

Abstract :

<p>&nbsp;</p> <p class="MsoNormal" style="text-align:justify;line-height:200%"><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">INTRODUCTION:<span style="mso-spacerun:yes">&nbsp; </span><span style="color:black;background:white">Meningiomas are neoplasms derived from arachnoidal cap cells in the meningeal coverings of the spinal cord and ain<span class="apple-converted-space">. &nbsp;</span>They constitute one of the most common benign intracranial tumours. MATERIAL AND METHODS: It was a single centre retrospective observational study of 126 cases from 2007 to 2016. RESULTS: </span></span><span lang="EN-IN" style="font-size:&#10;12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:&#10;Calii">Meningiomas accounted for 20.5% of all CNS lesions. Mean age of patients was 47.6 years. Females had higher predilection for meningioma. </span><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-fareast-font-family:Calii;mso-fareast-theme-font:minor-latin;mso-fareast-language:&#10;EN-US">The most common clinical symptom was headache (38.9%).</span><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-fareast-font-family:Calii"> </span><span lang="EN-IN" style="font-size:&#10;12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:&#10;Calii;mso-fareast-theme-font:minor-latin;mso-fareast-language:EN-US">Cereal convexity was the most favoured site (42.1%). </span><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-fareast-font-family:Calii">Grade I meningiomas were 85.7%, grade II were 11.9% and grade III were 2.4%. Transitional meningioma was most common variant (53.2%) followed by atypical type (11.1%) and meningothelial type (9.5%). </span><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-fareast-font-family:Calii;mso-fareast-theme-font:minor-latin;mso-fareast-language:&#10;EN-US">Males were found to have a much higher incidence of grade II meningiomas (7.9%) and grade III meningiomas (2.4%).</span><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;color:black;background:white"> </span><span lang="EN-IN" style="font-size:12.0pt;&#10;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:&#10;Calii">CONCLUSION: Histological variants of meningioma aid in prognostication and treatment.</span><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;&#10;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:black;background:white"><o:p></o:p></span></p>