Volume : 6, Issue : 12, December - 2017

CLINICAL EFFECTS OF LOCAL INFILTRATION OF AUTOLOGUS PLATELET SUPERNATANT IN SUPRASPINATUS TENDINOPATHIES

Dr Nandan Kumar Mishra, Dr Roshan Wade

Abstract :

Tendon injuries are a common presentation to the orthopaedic OPD. Supraspinatus tendinopathy is a common occurrence and commonly occurs at the “critical area” located between 1.25 - 2.5 cms proximal to site of insertion1. There is increasing interest in the use of autologous platelet concentrate or platelet rich plasma4. PRP is exogenously applied to soft tissues to promote wound healing and tissue sealing (4,5). <p class="MsoNormal" style="line-height:200%;mso-pagination:none;tab-stops:28.0pt 56.0pt 84.0pt 112.0pt 140.0pt 168.0pt 196.0pt 224.0pt 3.5in 280.0pt 308.0pt 336.0pt;
mso-layout-grid-align:none;text-autospace:none">  <p class="MsoNormal" style="line-height:200%;mso-pagination:none;tab-stops:28.0pt 56.0pt 84.0pt 112.0pt 140.0pt 168.0pt 196.0pt 224.0pt 3.5in 280.0pt 308.0pt 336.0pt;
mso-layout-grid-align:none;text-autospace:none">Materials and Methods<o:p></o:p> <p class="MsoNormal" style="line-height:200%;mso-pagination:none;tab-stops:28.0pt 56.0pt 84.0pt 112.0pt 140.0pt 168.0pt 196.0pt 224.0pt 3.5in 280.0pt 308.0pt 336.0pt;
mso-layout-grid-align:none;text-autospace:none"> <o:p></o:p> <p class="MsoNormal" style="line-height:200%;mso-pagination:none;tab-stops:28.0pt 56.0pt 84.0pt 112.0pt 140.0pt 168.0pt 196.0pt 224.0pt 3.5in 280.0pt 308.0pt 336.0pt;
mso-layout-grid-align:none;text-autospace:none">The study was a prospective study conducted at tertiary care hospital catering to both urban and rural population. The freshly prepared PRP was taken in syringe with needle no. 24 and around 2-3ml of PRP was injected at the site of tendon. At baseline, 1 month, 3months and 6 months the patients were assessed for pain and movement on the affected side with the help of Constant Murley score. <o:p></o:p> <p class="MsoNormal" style="line-height:200%;mso-pagination:none;tab-stops:28.0pt 56.0pt 84.0pt 112.0pt 140.0pt 168.0pt 196.0pt 224.0pt 3.5in 280.0pt 308.0pt 336.0pt;
mso-layout-grid-align:none;text-autospace:none">  <p class="MsoNormal" style="line-height:200%;mso-pagination:none;tab-stops:28.0pt 56.0pt 84.0pt 112.0pt 140.0pt 168.0pt 196.0pt 224.0pt 3.5in 280.0pt 308.0pt 336.0pt;
mso-layout-grid-align:none;text-autospace:none">Result<o:p></o:p> <p class="MsoNormal" style="line-height:200%;mso-pagination:none;tab-stops:28.0pt 56.0pt 84.0pt 112.0pt 140.0pt 168.0pt 196.0pt 224.0pt 3.5in 280.0pt 308.0pt 336.0pt;
mso-layout-grid-align:none;text-autospace:none">  <p class="MsoNormal" style="line-height:200%;mso-pagination:none;tab-stops:28.0pt 56.0pt 84.0pt 112.0pt 140.0pt 168.0pt 196.0pt 224.0pt 3.5in 280.0pt 308.0pt 336.0pt;
mso-layout-grid-align:none;text-autospace:none">Grade wise 63.3% cases had poor and 36.6% had fair shoulder function as baseline. This gradually improved at 1 month with 63.3% patients having fair function and 3.34% patients having good function at affected shoulder. At 3 months there was further improvement and 33.33% patients had good function, and 56.67% patients with fair function of shoulder. At 6 months. 9.09% had poor function whereas percentage of those with fair function increased marginally (59.09%) compared to 3 months. <o:p></o:p> <p class="MsoNormal" style="line-height:200%;mso-pagination:none;tab-stops:28.0pt 56.0pt 84.0pt 112.0pt 140.0pt 168.0pt 196.0pt 224.0pt 3.5in 280.0pt 308.0pt 336.0pt;
mso-layout-grid-align:none;text-autospace:none">  <p class="MsoNormal" style="line-height:200%;mso-pagination:none;tab-stops:28.0pt 56.0pt 84.0pt 112.0pt 140.0pt 168.0pt 196.0pt 224.0pt 3.5in 280.0pt 308.0pt 336.0pt;
mso-layout-grid-align:none;text-autospace:none">Conclusion<o:p></o:p> <p class="MsoNormal" style="line-height:200%;mso-pagination:none;tab-stops:28.0pt 56.0pt 84.0pt 112.0pt 140.0pt 168.0pt 196.0pt 224.0pt 3.5in 280.0pt 308.0pt 336.0pt;
mso-layout-grid-align:none;text-autospace:none">  <p class="MsoNormal" style="line-height:200%;mso-pagination:none;tab-stops:28.0pt 56.0pt 84.0pt 112.0pt 140.0pt 168.0pt 196.0pt 224.0pt 3.5in 280.0pt 308.0pt 336.0pt;
mso-layout-grid-align:none;text-autospace:none">We found significant improvement in shoulder function as the Constant-Murley score reduced significantly at 1 month (P<0.0001) and at 3 months (P<0.0001) from the baseline.<o:p></o:p> <p class="MsoNormal" style="line-height:200%;mso-pagination:none;tab-stops:28.0pt 56.0pt 84.0pt 112.0pt 140.0pt 168.0pt 196.0pt 224.0pt 3.5in 280.0pt 308.0pt 336.0pt;
mso-layout-grid-align:none;text-autospace:none">  <p class="MsoNormal" style="line-height:200%;mso-pagination:none;tab-stops:28.0pt 56.0pt 84.0pt 112.0pt 140.0pt 168.0pt 196.0pt 224.0pt 3.5in 280.0pt 308.0pt 336.0pt;
mso-layout-grid-align:none;text-autospace:none">

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Download PDF Journal DOI : 10.15373/2249555X

Cite This Article:

Dr Nandan Kumar Mishra, Dr Roshan Wade, CLINICAL EFFECTS OF LOCAL INFILTRATION OF AUTOLOGUS PLATELET SUPERNATANT IN SUPRASPINATUS TENDINOPATHIES, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : VOLUME-6, ISSUE-12, DECEMBER-2017