Volume : 7, Issue : 1, January - 2018

EVALUATING THE EFFICACY OF NANOCRYSTALLINE BETA-TRICALCIUM PHOSPHATE IN TYPE I COLLAGEN PLUG FOR PRESERVATION OF MANDIBULAR EXTRACTION SOCKETS- A PROSPECTIVE, CLINICAL AND RADIOGRAPHIC STUDY

Dr. Nisharudeen. K, Dr. Mohanavalli. S, Dr. Krishnakumar Raja. V. B

Abstract :

<p>&nbsp;</p> <p class="MsoNormal" style="margin-top:3.0pt"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-GB" style="font-size:14.0pt;line-height:200%;color:black">Context:</span></b><b style="mso-bidi-font-weight:normal"><span lang="EN-GB" style="font-size:14.0pt;&#10;line-height:200%;letter-spacing:1.0pt"><span style="mso-spacerun:yes">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span></span></b><b style="mso-bidi-font-weight:normal"><span lang="EN-IN" style="font-size:14.0pt;line-height:200%;color:#292526;mso-ansi-language:EN-IN;&#10;mso-fareast-language:EN-IN"><span style="mso-spacerun:yes">&nbsp;</span><o:p></o:p></span></b></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-IN" style="font-size:&#10;14.0pt;line-height:200%;color:#131313;mso-ansi-language:EN-IN;mso-fareast-language:&#10;EN-IN">Healing process after tooth extraction never results in complete restitution of the original alveolar bone volume due to physiologic resorption. Various methods have been tried in literature for preservation of the extraction socket. This study evaluates the efficacy of </span><span lang="EN-GB" style="font-size:14.0pt;line-height:200%">Beta-Tricalcium phosphate in type I collagen plug for preservation of mandibular extraction sockets.<span style="color:black"><o:p></o:p></span></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;color:black"><o:p>&nbsp;</o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-GB" style="font-size:14.0pt;line-height:200%;color:black">Aims and objectives:<o:p></o:p></span></b></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;color:black">Aim of this study is to evaluate the healing of extraction sockets preserved with </span><span lang="EN-GB" style="font-size:14.0pt;line-height:200%">Beta-Tricalcium phosphate in type I collagen plug clinically and radiographically and to compare them with normal healing sockets.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;color:black"><o:p>&nbsp;</o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;color:black"><o:p>&nbsp;</o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-GB" style="font-size:14.0pt;line-height:200%;color:black">Settings and Design:<o:p></o:p></span></b></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;color:black">Prospective, randomised controlled clinical trial with split mouth design was selected to avoid individual variations in the healing process.<span style="mso-spacerun:yes">&nbsp; </span><o:p></o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;color:black"><o:p>&nbsp;</o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-GB" style="font-size:14.0pt;line-height:200%;color:black">Methods and Material:<o:p></o:p></span></b></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;letter-spacing:1.0pt">10 systemically healthy adult patients, 22-32 years of age (mean age: 26.6 years), who underwent surgical removal of bilateral impacted third molars in the mandible was selected for the study. One side was grafted with test material and other was left to heal spontaneously as control side. Healing was evaluated clinically and radiographically using CBCT greyscale values. </span><span lang="EN-GB" style="font-size:14.0pt;line-height:200%;color:black"><o:p></o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;color:black"><o:p>&nbsp;</o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-GB" style="font-size:14.0pt;line-height:200%;color:black">Statistical analysis used:</span></b><b><span lang="EN-GB" style="font-size:14.0pt;&#10;line-height:200%"> <o:p></o:p></span></b></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;mso-bidi-font-weight:bold">Independent samples t-test was used to compare the mean differences in socket dimensions and mean CBCT grey scale values. Non-parametric Mann-Whitney test is used to compare the clinical attachment levels </span><span lang="EN-GB" style="font-size:14.0pt;&#10;line-height:200%;color:black"><o:p></o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;color:black"><o:p>&nbsp;</o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;color:black"><o:p>&nbsp;</o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;color:black"><o:p>&nbsp;</o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-GB" style="font-size:14.0pt;line-height:200%;color:black">Results:<o:p></o:p></span></b></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;color:black"><span style="mso-spacerun:yes">&nbsp;</span>Sites grafted with the study material when compared to control side showed<o:p></o:p></span></p> <p class="MsoListParagraphCxSpFirst" style="margin-top:3.0pt;mso-add-space:auto;&#10;text-indent:-.25in;mso-list:l0 level1 lfo1"><!--[if !supportLists]--><span lang="EN-GB" style="font-size:14.0pt;line-height:200%;color:black"><span style="mso-list:Ignore">1.<span style="font:7.0pt &quot;Times New Roman&quot;">&nbsp;&nbsp;&nbsp;&nbsp; </span></span></span><!--[endif]--><span lang="EN-GB" style="font-size:14.0pt;&#10;line-height:200%;color:black">Better clinical attachment levels<o:p></o:p></span></p> <p class="MsoListParagraphCxSpMiddle" style="margin-top:3.0pt;mso-add-space:auto;&#10;text-indent:-.25in;mso-list:l0 level1 lfo1"><!--[if !supportLists]--><span lang="EN-GB" style="font-size:14.0pt;line-height:200%;color:black"><span style="mso-list:Ignore">2.<span style="font:7.0pt &quot;Times New Roman&quot;">&nbsp;&nbsp;&nbsp;&nbsp; </span></span></span><!--[endif]--><span lang="EN-GB" style="font-size:14.0pt;&#10;line-height:200%;color:black">Significant reduction in alveolar crestal bone loss and <o:p></o:p></span></p> <p class="MsoListParagraphCxSpLast" style="margin-top:3.0pt;mso-add-space:auto;&#10;text-indent:-.25in;mso-list:l0 level1 lfo1"><!--[if !supportLists]--><span lang="EN-GB" style="font-size:14.0pt;line-height:200%;color:black"><span style="mso-list:Ignore">3.<span style="font:7.0pt &quot;Times New Roman&quot;">&nbsp;&nbsp;&nbsp;&nbsp; </span></span></span><!--[endif]--><span lang="EN-GB" style="font-size:14.0pt;&#10;line-height:200%;color:black">Better bone quality <o:p></o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;color:black"><o:p>&nbsp;</o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-GB" style="font-size:14.0pt;line-height:200%;color:black">Conclusions:<o:p></o:p></span></b></p> <p class="MsoNormal" style="margin-top:3.0pt"><span lang="EN-GB" style="font-size:&#10;14.0pt;line-height:200%;color:black">Results obtained showed that there is a significant improvement in quantity and quality of alveolar bone if preserved with </span><span lang="EN-GB" style="font-size:14.0pt;line-height:200%">Beta-Tricalcium phosphate in type I collagen plug, <span style="color:black">which is more suitable for future dental implant placement.<o:p></o:p></span></span></p>