Volume : 7, Issue : 1, January - 2018

Evaluation on whether Psoriasis Severity is Affected by the Lipid Profile in Indian Patients: A Hospital Based Study

Col. Dr Mahendra Singh Deora

Abstract :

<p>&nbsp;</p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;text-justify:inter-ideograph;line-height:normal;mso-layout-grid-align:&#10;none;text-autospace:none"><i style="mso-bidi-font-style:normal"><span style="font-size:10.0pt;font-family:&quot;Andalus&quot;,&quot;serif&quot;">Psoriasis is a lifelong chronic inflammatory skin disorder </span></i><i style="mso-bidi-font-style:&#10;normal"><span style="font-size:10.0pt;font-family:&quot;Andalus&quot;,&quot;serif&quot;;mso-fareast-font-family:&#10;MinionPro-Regular">characterized by increased T helper cell activity and associated with abnormal lipid metabolism</span></i><i style="mso-bidi-font-style:&#10;normal"><span style="font-size:10.0pt;font-family:&quot;Andalus&quot;,&quot;serif&quot;"> and reduced differentiation of keratinocytes. </span></i><i style="mso-bidi-font-style:&#10;normal"><span style="font-size:10.0pt;font-family:&quot;Andalus&quot;,&quot;serif&quot;;mso-fareast-font-family:&#10;MinionPro-Regular">Aim of<span style="mso-spacerun:yes">&nbsp; </span>study was to </span></i><i style="mso-bidi-font-style:normal"><span style="font-size:10.0pt;font-family:&#10;&quot;Andalus&quot;,&quot;serif&quot;">evaluate the lipid profile status </span></i><i style="mso-bidi-font-style:normal"><span style="font-size:10.0pt;font-family:&#10;&quot;Andalus&quot;,&quot;serif&quot;;mso-fareast-font-family:MinionPro-Regular">in patients with psoriasis and compare with healthy controls and whether it affects the severity of psoriasis. </span></i><i style="mso-bidi-font-style:normal"><span style="font-size:10.0pt;font-family:&quot;Andalus&quot;,&quot;serif&quot;">In conclusion we foundthat cholesterol, LDL-c and triglyceride levels are asreported previously to be higher in psoriasis patients while HDL-c levels are as reported previously to be low which makes adifference in the severity of psoriasis.</span></i><i style="mso-bidi-font-style:normal"><span style="font-size:10.0pt;font-family:&#10;&quot;Andalus&quot;,&quot;serif&quot;;mso-fareast-font-family:MinionPro-Regular"><o:p></o:p></span></i></p>