Volume : 7, Issue : 1, January - 2018

COMPARISON OF HYPERBARIC ROPIVACAINE AND HYPERBARIC BUPIVACAINE IN UNILATERAL SPINAL ANAESTHESIA

Dr. Rajeev Sharma, Dr. Pratibha Rathore, Dr. C K Vyas

Abstract :

<p>&nbsp;</p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span style="font-size:14.0pt;mso-bidi-font-family:Calii;mso-bidi-theme-font:minor-latin">OBJECTIVES: </span></b><span style="font-size:14.0pt;mso-bidi-font-family:Calii;&#10;mso-bidi-theme-font:minor-latin">To assess and compare the onset and duration of sensory and motor block, duration of analgesia, haemodynamic changes and requirement of first analgesia in post operative period<b style="mso-bidi-font-weight:&#10;normal"><u><o:p></o:p></u></b></span></p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span style="font-size:14.0pt;mso-bidi-font-family:Calii;mso-bidi-theme-font:minor-latin">METHODS: </span></b><span style="font-size:14.0pt;mso-bidi-font-family:Calii;&#10;mso-bidi-theme-font:minor-latin">After obtaining approval from the Institutional Ethics Committee, this prospective, randomized, double blind study was conducted in 50 patients of ASA physical status I /II, aged between 18 to 50 years undergoing elective unilateral lower limb surgeries under unilateral SAB. Patients were randomly allocated into two groups using chit in box method.<o:p></o:p></span></p> <p class="MsoNormal"><span style="font-size:14.0pt;mso-bidi-font-family:Calii;&#10;mso-bidi-theme-font:minor-latin">Group B (n=25):7.5mg of 0.375% hyperbaric inj. bupivacaine (2ml)<o:p></o:p></span></p> <p class="MsoNormal"><span style="font-size:14.0pt;mso-bidi-font-family:Calii;&#10;mso-bidi-theme-font:minor-latin">Group R (n=25): 10mg of 0.5% hyperbaric inj. ropivacaine (2ml).<o:p></o:p></span></p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span style="font-size:14.0pt;mso-bidi-font-family:Calii;mso-bidi-theme-font:minor-latin">RESULTS :</span></b><span style="font-size:14.0pt;mso-bidi-font-family:Calii;&#10;mso-bidi-theme-font:minor-latin">The mean onset of sensory block and motor block is earlier (p&lt;0.05) in group B (sensory 2.98 &plusmn; 0.54 min, motor 2.74 &plusmn; 1.70 min) as compared to group R (sensory<span style="mso-spacerun:yes">&nbsp; </span>5.16 &plusmn; 1.74, motor 4.60 &plusmn; 1.979 min). Mean duration of analgesia was significantly prolonged in group B (129.28 &plusmn; 41.312 min) compared to group R (107.40 &plusmn; 30.28 min). The mean duration of motor block was significantly longer in group B (218.76 &plusmn; 64.598) as compared to group R (139.60 &plusmn; 31.02 min). Proportion of unilateral block<span style="mso-spacerun:yes">&nbsp; </span>in<span style="mso-spacerun:yes">&nbsp; </span>patients<span style="mso-spacerun:yes">&nbsp; </span>were significantly higher (80%) in group B as compared to group R (48%) according to sensory block in non operative side .First analgesia time was shorter in group R (173 &plusmn; 115.8 min) than in group B (289 &plusmn; 146.4 min).<o:p></o:p></span></p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span style="font-size:14.0pt;mso-bidi-font-family:Calii;mso-bidi-theme-font:minor-latin">Conclusion:</span></b><span style="font-size:14.0pt;mso-bidi-font-family:Calii;mso-bidi-theme-font:minor-latin"> The faster onset and longer duration of block was observed in the bupivacaine group, while hyperbaric ropivacaine provides a more selective unilateral block with stable haemodynamic variables.<o:p></o:p></span></p>