Volume : 7, Issue : 2, February - 2018

PROFILE OF HYPONATREMIA IN ELDERLY: STUDY FROM A TERTIARY TEACHING HOSPITAL OF EASTERN INDIA

Dr Prasanna Kumar Rathor, Dr Ambily K. , Prof. Dhirendra Nath Maharana, Dr. Manoranjan Behera

Abstract :

<p>&nbsp;</p> <p class="MsoNormal" style="line-height:200%"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&#10;&quot;Times New Roman&quot;,&quot;serif&quot;">Background</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">: Hyponatremia is the most common electrolyte disorderparticularly in elderly population and among hospitalized patients.<o:p></o:p></span></p> <p class="MsoNormal" style="line-height:200%"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&#10;&quot;Times New Roman&quot;,&quot;serif&quot;">Objectives</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">: To investigate clinical manifestations, severity, etiological factors, comorbid conditions and outcome following treatment in elderly hyponatremic patients.<o:p></o:p></span></p> <p class="MsoNormal" style="line-height:200%"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&#10;&quot;Times New Roman&quot;,&quot;serif&quot;">Methodology</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">: Elderly patients (&ge;60years) having serum sodium below 135mmol/L at the time of presentation or fall during hospital stay were enrolled.<o:p></o:p></span></p> <p class="MsoNormal" style="line-height:200%"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&#10;&quot;Times New Roman&quot;,&quot;serif&quot;">Results</span></b><span lang="EN-IN" style="font-size:&#10;12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">: Of total 50 patients, profound hyponatremia was found in 50% cases. 72% patients were symptomatic out of which altered sensorium was the most common presentation(41.6%) .All patients of profound hyponatremia were symptomatic.Euvolemia, hypervolemia and hypovolemia was found in 54 %, 24 %, 22% cases respectively. Drug induced hyponatremia was the commonest etiology followed by SIADH. Loop diuretics were major culprit.Hypertension was the most common comorbid condition followed by diabetes mellitus.Multiple comrbidites were found in 34 % cases. Mortality was recorded in 6 % cases.<o:p></o:p></span></p> <p class="MsoNormal" style="line-height:200%"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&#10;&quot;Times New Roman&quot;,&quot;serif&quot;">Conclusion</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"> : Hyponatremia in elderly is multifactorial and is associated with comorbidities. Diuretics should be used with caution in elderly.<o:p></o:p></span></p>