Volume : 7, Issue : 2, February - 2018

ANALYSIS OF SERUM LEVELS OF VITAMIN D AMONG PATIENTS WITH NASAL POLYPS IN KASHMIRI POPULATION

Dr Omar Mohammad Shafi, Dr Abdul Hanan, Dr Aezaz Ahmad Bhat

Abstract :

<p>&nbsp;</p> <p class="MsoNormal"><b>Background: </b>Nasal polyps (CRSwNP) is a common chronic conditions of the nasal or paranasal sinus mucosa. Vitamin D deficiency, has been linked to a high rate of both infectious and inflammatory diseases, including those of the upper and lower airways. <o:p></o:p></p> <p class="MsoNormal"><b>Aim: </b>In this study, the association between plasma 25-hydroxy vitamin D (25[OH]D) levels in patients with nasal polyps was analysed. <o:p></o:p></p> <p class="MsoNormal"><b>Material and method</b><span style="mso-bidi-font-weight:&#10;bold">: <span style="mso-spacerun:yes">&nbsp;</span>This prospective study was conducted on patients 18-65 years of age who came to ENT OPD at GMC Srinagar and associated SMHS hospital, with nasal polyps from July 2015 to July 2017 </span>.Sixty patients (31 male and 29 female), were enrolled in this study. <o:p></o:p></p> <p class="MsoNormal"><b>Results: </b>Serum levels of 25 (OH) vitamin D were measured by using a 25 (OH) vitamin D enzyme immune assay kit. There were no statistically significant differences between the control and study groups in plasma 25(OH) D levels, gender, or age (p&lt;0.05). <o:p></o:p></p> <p class="MsoNormal"><b>Conclusions: </b>This study did not show an association between serum plasma levels of 25-hydroxy vitamin D and bone defect with nasal polyposis among patients living in Kashmir.<o:p></o:p></p>