Volume : 7, Issue : 2, February - 2018

ARTIFICIAL SALIVA SUBSTITUTES EVALUATION: THE ROLE OF SOME CHEMICAL-PHYSICAL PROPERTIES

Pier Luigi Foglio Bonda, Marco Farinone, Franco Pattarino, Andrea Foglio Bonda

Abstract :

<p>&nbsp;</p> <p class="MsoNormal" style="margin-bottom:3.0pt;text-align:justify;line-height:&#10;200%;mso-outline-level:1"><span style="mso-ansi-language:EN-US">The evaluation of some chemical-physical properties of artificial saliva substitutes easily available on the E.U. market, such as viscosity, pH, buffering capacity, superficial tension, density and spinnbarkeit and compare the results with human natural saliva bibliographic data.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%;mso-pagination:&#10;none;mso-outline-level:1;mso-layout-grid-align:none;text-autospace:none"><span lang="EN-GB" style="mso-ansi-language:EN-GB">All the saliva substitute products were purchased on the net using University students as customer models. Viscosity and density measurement were performed using a falling ball type viscometer (Anton Paar</span><span lang="EN-GB" style="font-family:Symbol;&#10;mso-ascii-font-family:&quot;Times New Roman&quot;;mso-hansi-font-family:&quot;Times New Roman&quot;;&#10;mso-ansi-language:EN-GB;mso-char-type:symbol;mso-symbol-font-family:Symbol"><span style="mso-char-type:symbol;mso-symbol-font-family:Symbol">&Ograve;</span></span><span lang="EN-GB" style="mso-ansi-language:EN-GB"> - Lovis 200 ME); Surface tension by using a tensiometer (KSV - Sigma 703d), while spinnbarkeit by own instrument built for the purpose. Buffering capacity was determined according to method described in literature.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%"><span lang="EN-GB" style="mso-ansi-language:EN-GB">Viscosity values ranging from a min. value of 1.682 mPa</span><span lang="EN-GB" style="font-family:Symbol;mso-ascii-font-family:&#10;&quot;Times New Roman&quot;;mso-hansi-font-family:&quot;Times New Roman&quot;;mso-ansi-language:&#10;EN-GB;mso-char-type:symbol;mso-symbol-font-family:Symbol"><span style="mso-char-type:symbol;mso-symbol-font-family:Symbol">&times;</span></span><span lang="EN-GB" style="mso-ansi-language:EN-GB">s to a maximum value of 21.727 mPa</span><span lang="EN-GB" style="font-family:Symbol;mso-ascii-font-family:&quot;Times New Roman&quot;;&#10;mso-hansi-font-family:&quot;Times New Roman&quot;;mso-ansi-language:EN-GB;mso-char-type:&#10;symbol;mso-symbol-font-family:Symbol"><span style="mso-char-type:symbol;&#10;mso-symbol-font-family:Symbol">&times;</span></span><span lang="EN-GB" style="mso-ansi-language:EN-GB">s, <i style="mso-bidi-font-style:normal">CMC </i>based products have the highest viscosity values. Four products (Saliveze</span>^{<span lang="IT" style="font-family:Symbol;mso-ascii-font-family:&quot;Times New Roman&quot;;&#10;mso-hansi-font-family:&quot;Times New Roman&quot;;mso-char-type:symbol;mso-symbol-font-family:&#10;Symbol"><span style="mso-char-type:symbol;mso-symbol-font-family:Symbol">&Ograve;</span></span>}<span lang="EN-GB" style="mso-ansi-language:EN-GB">, Xerotin</span>^{<span lang="IT" style="font-family:Symbol;mso-ascii-font-family:&quot;Times New Roman&quot;;mso-hansi-font-family:&#10;&quot;Times New Roman&quot;;mso-char-type:symbol;mso-symbol-font-family:Symbol"><span style="mso-char-type:symbol;mso-symbol-font-family:Symbol">&Ograve;</span></span>}<span lang="EN-GB" style="mso-ansi-language:EN-GB">, Saliva Orthana</span>^{<span lang="IT" style="font-family:Symbol;mso-ascii-font-family:&quot;Times New Roman&quot;;&#10;mso-hansi-font-family:&quot;Times New Roman&quot;;mso-char-type:symbol;mso-symbol-font-family:&#10;Symbol"><span style="mso-char-type:symbol;mso-symbol-font-family:Symbol">&Ograve;</span></span>}<span lang="EN-GB" style="mso-ansi-language:EN-GB"> and Xerostom</span>^{<span lang="IT" style="font-family:Symbol;mso-ascii-font-family:&quot;Times New Roman&quot;;&#10;mso-hansi-font-family:&quot;Times New Roman&quot;;mso-char-type:symbol;mso-symbol-font-family:&#10;Symbol"><span style="mso-char-type:symbol;mso-symbol-font-family:Symbol">&Ograve;</span></span>}<span lang="EN-GB" style="mso-ansi-language:EN-GB">) have a pH value higher than 6.00. Buffering capacity values ranging from a min. value of <span style="color:black">0.909 mmol H⁺/L</span> to 3.333 <span style="color:black">mmol H⁺/L</span> reveal oad results between the samples.</span><span style="mso-ansi-language:&#10;EN-US"><o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%;mso-pagination:&#10;none;mso-layout-grid-align:none;text-autospace:none"><span lang="EN-GB" style="mso-ansi-language:EN-GB">Form our data and literature review lower values of viscosity and surface tension can be ascribed as the most important features that obtain patient compliance in artificial saliva substitutes. Nevertheless, products selection had to be based on market availability and personal preference.<o:p></o:p></span></p>