Volume : 7, Issue : 3, March - 2018

Association of Microalbuminuria with Systolic and Diastolic Blood Pressure in Hypertensive patients

Dr. Sujata Agarwal, Dr. Surender Mittal, Dr. G. N. Saxena

Abstract :

<p>&nbsp;</p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:&#10;normal;mso-layout-grid-align:none;text-autospace:none"><b><span style="font-size:20.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-bidi-font-style:&#10;italic">Background:</span></b><b><span style="font-size:10.0pt;font-family:&#10;&quot;Times New Roman&quot;,&quot;serif&quot;;mso-bidi-font-style:italic"> </span></b><span style="font-size:16.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-bidi-font-weight:&#10;bold;mso-bidi-font-style:italic">Microalbuminuria is an established marker of kidney as well as cardiovascular damage in diabetics but its association in hypertension is not very well known</span><span style="font-size:16.0pt;&#10;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-bidi-font-style:italic">.<span style="mso-spacerun:yes">&nbsp; </span>As hypertension is a major cause of morbidity and mortality all over world, especially in India. Present study was undertaken to correlate Microalbuminuria with systolic and diastolic hypertension.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:&#10;normal;mso-layout-grid-align:none;text-autospace:none"><b><span style="font-size:20.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-bidi-font-style:&#10;italic"><o:p>&nbsp;</o:p></span></b></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:&#10;normal;mso-layout-grid-align:none;text-autospace:none"><b><span style="font-size:20.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-bidi-font-style:&#10;italic">Methodology: </span></b><span style="font-size:16.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-bidi-font-style:italic">Thirty patients of hypertension coming to OPD/Wards of MGUMST, Jaipur who fulfilled the inclusion criteria were recruited. They were subjected to detailed history, clinical examination &amp; diagnostic tests. Data analysis was done using SPSS software.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:&#10;normal;mso-layout-grid-align:none;text-autospace:none"><b><span style="font-size:20.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-bidi-font-style:&#10;italic"><o:p>&nbsp;</o:p></span></b></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:&#10;normal;mso-layout-grid-align:none;text-autospace:none"><b><span style="font-size:20.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-bidi-font-style:&#10;italic">Results:</span></b><span style="font-size:16.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-bidi-font-style:italic"> Microalbuminuria has a stronger association with diastolic blood pressure (BP). As 100% patients with stage 2 diastolic BP had microalbuminuria ( p &lt;0.05); compared with </span><span style="font-size:&#10;16.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">84.6% <span style="mso-spacerun:yes">&nbsp;</span>in Stage II systolic hypertension (p value &gt; 0.05).<span style="mso-bidi-font-style:italic"><o:p></o:p></span></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:&#10;normal;mso-layout-grid-align:none;text-autospace:none"><b><span style="font-size:20.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-bidi-font-style:&#10;italic"><o:p>&nbsp;</o:p></span></b></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:&#10;normal;mso-layout-grid-align:none;text-autospace:none"><b><span style="font-size:20.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-bidi-font-style:&#10;italic">Conclusion:</span></b><b><span style="font-size:10.0pt;font-family:&#10;&quot;Times New Roman&quot;,&quot;serif&quot;;mso-bidi-font-style:italic"> </span></b><span style="font-size:16.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-bidi-font-style:&#10;italic">In hypertension there is a higher prevalence of microalbuminuria in patients with raised diastolic BP compared to systolic BP. We recommend screening for Microalbuminuria in all hypertensive patients as it is an important prognostic marker for cardiovascular as well as renal morbidity &amp; mortaity. This will also guide us towards selection of appropriate drugs and formulating preventive strategy.<o:p></o:p></span></p>