Volume : 7, Issue : 3, March - 2018

LIVER DISORDER DURING PREGNANCY: A STUDY OF CLINICAL PROFILE IN A TERTIARY CARE HOSPITAL

Dr. Ashish Zarariya, Dr. Yogesh Kamble

Abstract :

<p>&nbsp;</p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span style="font-size:16.0pt;line-height:115%">Background:</span></b><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;"> The spectrum of liver disorder during pregnancy is varied from asymptomatic pregnant woman to a fulminant form with life threatening complications. Commonly liver disorder manifests as jaundice. This study aims to analyze the incidence, risk facors, causes of liver disease, clinical presentation, complications and maternal-fetal outcome.<o:p></o:p></span></p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">Methods: </span></b><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">A prospective observational type of study conducted on 100 patients with jaundice attending antenatal clinic in our hospital over a period of one year.<o:p></o:p></span></p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">Results: </span></b><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">A total 100 cases of liver diseases complicating pregnancies were recorded out of 30,096 deliveries (0.33%).Viral hepatitis ( 71%) and HELLP syndrome (21%) accounted for majority of cases. Hepatitis E (38%) was the most common cause of liver disease and leads to high maternal-fetal morbidity and mortality.<o:p></o:p></span></p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">Conclusion: </span></b><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">Liver disease in pregnancy have a non specific presentation. Appropriate supportive management and policy of early delivery will help in improving maternal and fetal outcomes in pregnant women with liver disease.<o:p></o:p></span></p>