Volume : 7, Issue : 5, May - 2018

COMPARATIVE STUDY OF INTRATHECAL MORPHINE WITH BUPIVACAINE / INTRATHECAL BUPIVACAINE ON POSTOPERATIVE ANALGESIA FOR CESAREAN SECTION

Dr. Naghma E Sehar, Dr. Nirmala B. C, Dr. Anshika Gier, Dr. Mahalaximi M Baddi, Dr. Faiz Ahsan

Abstract :

<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:&#10;150%;mso-layout-grid-align:none;text-autospace:none"><b><span style="font-size:12.0pt;line-height:150%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">BACKGROUND<o:p></o:p></span></b></p> <p class="MsoNormal" style="line-height:normal"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Postoperative analgesia enables a faster rehabilitation, and reduces hospital stay. </span><span style="font-size: 12pt; font-family: &quot;Times New Roman&quot;, serif;">Intrathecal morphine provides slow onset and long-duration spinal analgesia. </span><span style="font-size:12.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:#292526">The procedure is simple, quick, and with a relatively low risk of technical complications or failure.</span><span style="font-size: 12pt; font-family: &quot;Times New Roman&quot;, serif;"><o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:&#10;normal;tab-stops:291.0pt;mso-layout-grid-align:none;text-autospace:none"><b><span style="font-size:12.0pt;font-family:&#10;&quot;Times New Roman&quot;,&quot;serif&quot;">AIM&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <o:p></o:p></span></b></p> <p class="MsoNormal" style="line-height:normal"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">To evaluate the quality of analgesia and the severity of side effects of low dose intrathecal morphine with low dose Bupivacaine for cesarean section.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:&#10;normal;mso-layout-grid-align:none;text-autospace:none"><b><span style="font-size:12.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">METHODOLOGY</span></b><span style="font-size:12.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">:<o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:&#10;normal;mso-layout-grid-align:none;text-autospace:none"><span style="font-size:&#10;12.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">&nbsp;</span></p> <p class="MsoNoSpacing"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">The study is an open randomized controlled study. 80 ASA physical status I and II term parturients undergoing cesarean delivery with spinal anesthesia were included in the study.Patients were randomized in 2 groups. All pregnancyinduced medical illness and cases with other medical diseases were excluded from the study.<o:p></o:p></span></p> <p class="MsoNoSpacing"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Group 1 (Study Group) received 1.8ml of intrathecal Bupivacaine 0.5% (H) with Morphine 0.1 mg (0.1ml).<o:p></o:p></span></p> <p class="MsoNormal"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Group 2 (Control Group) received 1.8ml of intrathecal Bupivacaine 0.5% (H) with 0.1ml sterile water.<o:p></o:p></span></p> <p class="MsoNormal"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Patients were followed up postoperatively until rescue analgesic was given.VAS score was used to assess pain. Once VAS score was 4, rescue analgesic was given.Patients received intravenous Paracetamol and intravenous Tramadol for analgesia. The time taken from spinal anesthesia till the rescue analgesia was recorded as duration of analgesia.<o:p></o:p></span></p> <p class="MsoNoSpacing"><b><span style="font-size:12.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">CONCLUSION:<o:p></o:p></span></b></p> <p class="MsoNoSpacing"><b><span style="font-size:12.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">&nbsp;</span></b></p> <p class="MsoNoSpacing"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Study group had a longer duration of analgesia when compared to control group.<o:p></o:p></span></p>