Volume : 7, Issue : 6, June - 2018

EVALUATION OF INTUBATING CONDITIONS WITH ROCURONIUM BY PRIMING TECHNIQUE. A RANDOMIZED DOUBLE BLIND STUDY.

Dr. Sangeetha Rao. Dara, Dr. Madhu Priya. Vempalli

Abstract :

<p>&nbsp;BACKGROUND: a prospective, randomized, double-blind study was designed to evaluate the effects of priming</p> <div>technique with rocuronium omide for intubation in adult patients undergoing surgical procedures.</div> <div>METHODS: sixty adult patients of 20-60 years of age with asa-1 physical status posted for surgical procedures were divided in to two</div> <div>groups. group c received normal saline (2ml) as priming dose and group p received 0.06mg/kg rocuronium (2 ml) as priming dose and after</div> <div>3 minutes intubating dose group c received 6 mg /kg (5 ml) group p received the 5.4 mg /kg (5 ml) as intubating dose .muscle relaxation was</div> <div>assessed with nerve stimulator for every 10 seconds and assessed visually for loss of adduction of thumb and disappearance of t1 of train of</div> <div>four (TOF) stimuli. By this we can note the onset time of intubation (Ti) and intubating conditions were assessed buy cooper et al scoring</div> <div>system. Any adverse effects were also noted.</div> <div>RESULTS: The mean onset of intubation time (Ti) in the group P was 52.33&plusmn;6.79 sec, in the group C was 95.67&plusmn;11.04 sec ,P value is 0.00 it is</div> <div>highly signi􀃶cant. Minimum Ti is 80 sec. and maximum Ti is 120 sec. intubation scores as per &ldquo;cooper et al scoring&rdquo; were 8 or 9 in both the</div> <div>groups. There were no incidences of weakness, aspiration, adycardia, ptosis, hypotension, in either of the groups during study</div> <div>observation.</div> <div>CONCLUSION: administration of Priming dose of rocuronium before the intubating dose causes the onset of neuromuscular block is rapid</div> <div>and onset time of intubation is became comparable to that of suxamethonium with excellent intubating conditions and without adverse</div> <div>effects.</div>