Volume : 7, Issue : 6, June - 2018

A CLINICAL TRIAL COMPARING INTRA VAGINAL MISOPROSTOL (PGE1) AND INTRA CERVICAL DINOPROSTONE ( PGE2 ) FOR CERVICAL RIPENING

Dr. R. G. Suresh Kumar, Dr. R. Sumathi

Abstract :

<p class="MsoNormal" style="margin-top:0in;margin-right:2.15pt;margin-bottom:&#10;6.0pt;margin-left:0in;text-align:justify;line-height:150%">In the present trial, Misoprostol(PGE1) and Dinoprostone(PGE2) are compared for their efficacy in pre - induction cervical ripening. After informed consent, 100 patients<span style="mso-spacerun:yes">&nbsp; </span>were randomized to receive either Dinoprostone gel int0.5mg inracervically or Misoprostol tablet 25 mcg intravginally. After 8 hrs, change in Bishops score recorded. During the study it is found that, change in Bishops score is significantly more and induction to delivery interval is significantly less in Misoprostol group. The incidence of side effects is similar in both the groups. It is concluded that a single dose of intravaginal Misoprostol is an efficacious, convenient and inexpensive medication for ripening the unfavourable cervix.</p>