Volume : 7, Issue : 5, May - 2018

Clinico-mycological profile of Dermatomycosis in Hadoti Region.

Dr. Bhanu Prakash Gupta, Dr. Naveen Saxena, Dr. Anita E Chand, Dr. Saurabh Sharma

Abstract :

<p class="MsoNormal" style="margin-bottom:12.0pt;text-align:justify"><b><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;color:black">Introduction</span></b><span style="font-size:12.0pt;line-height:&#10;115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:black">: Dermatophytes are by far the most significant fungi because of their<span style="mso-spacerun:yes">&nbsp; </span>widespread<span style="mso-spacerun:yes">&nbsp; </span>involvement<span style="mso-spacerun:yes">&nbsp; </span>of<span style="mso-spacerun:yes">&nbsp; </span>population <span style="mso-spacerun:yes">&nbsp;</span>and their<span style="mso-spacerun:yes">&nbsp; </span>prevalence<span style="mso-spacerun:yes">&nbsp; </span>all<span style="mso-spacerun:yes">&nbsp; </span>over the<span style="mso-spacerun:yes">&nbsp; </span>world.They are assuming greater significance both in developed and developing countries. Hot and humid climate in the tropical and subtropical countries like India makes dermatophytosis a very common superficial<span style="mso-spacerun:yes">&nbsp; </span>fungal<span style="mso-spacerun:yes">&nbsp;&nbsp; </span>skin<span style="mso-spacerun:yes">&nbsp; </span>infection. <o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:12.0pt;text-align:justify"><b><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Aims and objective: </span></b><span style="font-size:12.0pt;line-height:115%;&#10;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:black">The present study was undertaken to </span><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">detect prevalence and mycological profile of dermatomycosis which include Dermatophyte, Pityriasisversicolor and Candidiasis<span style="mso-spacerun:yes">&nbsp; </span>inhadoti region.<b><o:p></o:p></b></span></p> <p class="NoList1CxSpFirst" style="margin-bottom:0in;margin-bottom:.0001pt;&#10;mso-add-space:auto;text-align:justify;mso-pagination:none;text-autospace:none"><b><span lang="RU" style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Materials and Methods</span></b><span lang="RU" style="font-size:12.0pt;line-height:115%;&#10;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">: </span><span style="font-size:12.0pt;&#10;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:black;mso-ansi-language:&#10;EN-US">A<span style="mso-spacerun:yes">&nbsp; </span>total<span style="mso-spacerun:yes">&nbsp; </span>of 100 <span style="mso-spacerun:yes">&nbsp;</span>patients<span style="mso-spacerun:yes">&nbsp;&nbsp; </span>of dermatophytosisfrom skin department were<span style="mso-spacerun:yes">&nbsp; </span>studied.Skin,nail and hair specimens taken from the patients were processedby potassium hydroxide preparation(KOH) for direct microscopy and culture.<o:p></o:p></span></p> <p class="NoList1CxSpLast" style="margin-bottom:0in;margin-bottom:.0001pt;&#10;mso-add-space:auto;text-align:justify;mso-pagination:none;text-autospace:none"><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;color:black;mso-ansi-language:EN-US"><o:p>&nbsp;</o:p></span></p> <p class="MsoNormal" style="margin-top:0in;margin-right:-14.15pt;margin-bottom:&#10;0in;margin-left:0in;margin-bottom:.0001pt;text-align:justify;mso-pagination:&#10;none;mso-layout-grid-align:none;text-autospace:none"><b><span style="font-size:&#10;12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:black">Result:</span></b><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;color:black">Dermatophytosis was more common in the age group of 21-30 years (28%) and in males (64%).<span style="mso-spacerun:yes">&nbsp; </span>65 cases (65%) were positive by both microscopy and culture.Five cases(5%) were negative by microscopy but culture positive.Tineacorporis 45 (45%) was the commonest clinical type followed by Tineacruris<span style="mso-spacerun:yes">&nbsp; </span>19(19%).Overall out of the 70 (70%) culture isolates,<i style="mso-bidi-font-style:normal">Trichophytonruum</i> was the most common isolate with 33</span><span style="font-size:12.0pt;line-height:115%;&#10;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"> (47.14%)<span style="color:black">cases followed<span style="mso-spacerun:yes">&nbsp; </span>by<i style="mso-bidi-font-style:&#10;normal">Malesseziaspecies</i> with 13</span>(18.57%)<span style="color:black"> cases,<i style="mso-bidi-font-style:normal">Candida</i>species12</span>(17.14%)<span style="color:black">cases,<i style="mso-bidi-font-style:normal">Trichophytonmentagrophyte</i><span style="mso-spacerun:yes">&nbsp; </span>with 6</span> (8.57%)<span style="color:black"> cases.<o:p></o:p></span></span></p> <p class="MsoNormal" style="margin-top:0in;margin-right:-14.15pt;margin-bottom:&#10;0in;margin-left:0in;margin-bottom:.0001pt;text-align:justify;mso-pagination:&#10;none;mso-layout-grid-align:none;text-autospace:none"><span style="font-size:&#10;12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:black"><o:p>&nbsp;</o:p></span></p> <p class="MsoNormal" style="margin-top:0in;margin-right:-14.15pt;margin-bottom:&#10;0in;margin-left:0in;margin-bottom:.0001pt;text-align:justify;mso-pagination:&#10;none;mso-layout-grid-align:none;text-autospace:none"><b><span style="font-size:&#10;12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:black">Conclusion:</span></b><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">males are predominantly affected.<i style="mso-bidi-font-style:normal"><span style="color:black">Trichophytonruum</span></i><span style="color:black"> was the most common isolate.<o:p></o:p></span></span></p>