Volume : 7, Issue : 7, July - 2018

High-volume low-concentration intraperitoneal bupivacaine for post-laparoscopic cholecystectomy analgesia : A prospective randomised controlled study.

Dr. Jigyasa Shahani

Abstract :

<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:&#10;normal;mso-layout-grid-align:none;text-autospace:none"><span lang="EN-IN" style="font-size:16.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;color:black;&#10;background:white">Pain is considerable after laparoscopic cholecystectomy. </span><span lang="EN-IN" style="font-size:16.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">This study was conducted to evaluate results of high-volume lowconcentration bupivacaine for post</span><span lang="EN-IN" style="font-size:16.0pt;font-family:&#10;&quot;ZapfElliptical711BT-Roman&quot;,&quot;serif&quot;;mso-ascii-font-family:&quot;Times New Roman&quot;;&#10;mso-bidi-font-family:&quot;Times New Roman&quot;">‑</span><span lang="EN-IN" style="font-size:16.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">operative analgesia in Laparoscopic Cholecystectomy. Sixty patients undergoing LC were included in thisstudy. Patients were divided into two (<i>n </i>= 30) groups. In Group S intraperitoneal irrigation was done with 300 ml of normal saline. In Group B 25 ml of 0.5% (125 mg) bupivacaine was added to 275 mlof normal saline for intraperitoneal irrigation during and after surgery. Post</span><span lang="EN-IN" style="font-size:16.0pt;font-family:&quot;MS Gothic&quot;;mso-ascii-font-family:&#10;&quot;Times New Roman&quot;;mso-bidi-font-family:&quot;Times New Roman&quot;">‑</span><span lang="EN-IN" style="font-size:16.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">operative painassessment,duration of analgesia (DOA),total rescue analgesic requirement, nausea andvomiting were recorded for the initial 24 h post</span><span lang="EN-IN" style="font-size:16.0pt;font-family:&quot;MS Gothic&quot;;mso-ascii-font-family:&#10;&quot;Times New Roman&quot;;mso-bidi-font-family:&quot;Times New Roman&quot;">‑</span><span lang="EN-IN" style="font-size:16.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">operatively. <span style="mso-bidi-font-weight:bold">I</span>n Group Bmean DOA was more and cumulativerequirement of rescue analgesicwas less than that in Group B. There was no significant difference in incidence of nausea and vomiting between the groups. High</span><span lang="EN-IN" style="font-size:16.0pt;font-family:&quot;MS Gothic&quot;;&#10;mso-ascii-font-family:&quot;Times New Roman&quot;;mso-bidi-font-family:&quot;Times New Roman&quot;">‑</span><span lang="EN-IN" style="font-size:16.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">volume low</span><span lang="EN-IN" style="font-size:16.0pt;font-family:&quot;MS Gothic&quot;;&#10;mso-ascii-font-family:&quot;Times New Roman&quot;;mso-bidi-font-family:&quot;Times New Roman&quot;">‑</span><span lang="EN-IN" style="font-size:16.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">concentrationof intraperitoneal bupivacaine significantly increases post</span><span lang="EN-IN" style="font-size:16.0pt;font-family:&quot;MS Gothic&quot;;mso-ascii-font-family:&#10;&quot;Times New Roman&quot;;mso-bidi-font-family:&quot;Times New Roman&quot;">‑</span><span lang="EN-IN" style="font-size:16.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">operative DOA and reduces opioidrequirement after LC.<o:p></o:p></span></p>