Volume : 7, Issue : 7, July - 2018

Study of Gestational Trophoblastic Diseases

Dr. Amrita Jain, Dr. Rekha G Daver, Dr. Rangan Bhattacharya

Abstract :

<p class="MsoNormal" style="line-height:200%"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-IN" style="font-size:12.0pt;line-height:200%">Introduction:</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:200%"> Gestational trophoblastic disease (GTD) is a group of conditions that arise from trophoblastic tissue after fertilization. Published literature on GTD from the Indian subcontinent is minimal. Hence there is a need to evaluate the risk factors, complications, management, outcome of the condition.<o:p></o:p></span></p> <p class="MsoNormal" style="line-height:200%"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-IN" style="font-size:12.0pt;line-height:200%">Methods:</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;mso-bidi-font-family:&quot;Times New Roman&quot;">It is a retrospective study of GTD managed at our hospital from April 2015 to October 2016. <o:p></o:p></span></p> <p class="MsoNormal" style="line-height:200%"><b style="mso-bidi-font-weight:&#10;normal"><span lang="EN-IN" style="font-size:12.0pt;line-height:200%">Results:</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:200%"> The incidence was 0.27%. 7 were complete, 3 partial, 2 invasive moles, 1 PSTT and 1 choriocarcinoma. Age group of presentation ranged from 20-36 years. 28.57% primigravidae</span><span style="font-size:12.0pt;line-height:200%;mso-ansi-language:EN-US">, </span><span lang="EN-IN" style="font-size:12.0pt;line-height:200%">35.7% presented in first trimester. 10 had vaginal bleeding, 4 were detected incidentally. 4 cases had vomiting and 3, pain abdomen. Anaemia, theca lutein cysts, hyperthyroidism, hypertension and mortality were reported. Treatment options were surgical and medical.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:8.3pt;line-height:200%;background:white"><b style="mso-bidi-font-weight:normal"><span lang="EN-IN" style="font-size:12.0pt;&#10;line-height:200%">Conclusion:</span></b><span lang="EN-IN" style="font-size:12.0pt;&#10;line-height:200%"> GTD has a rising incidence. With the use of better diagnostic modalities, the condition can be detected early and treated appropriately. <o:p></o:p></span></p>