Volume : 7, Issue : 8, August - 2018

Study of prevalence of extrapulmonary tuberculosis and sputum positive pulmonary tuberculosis with its chest roentgenographic patterns among patients in a tertiary care hospital

Bhushan C Shetty, Anoop Shetty

Abstract :

<p class="MsoNormal" style="text-align:justify;line-height:200%"><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Introduction :</span><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-fareast-font-family:&quot;Times New Roman&quot;">Tuberculosis (TB) remains one of the major global health threats leading to morbidity and mortality <sup>(1,2).</sup> One in three persons across the world representing 2&ndash;3 billion individuals are known to be infected with Mycobacterium Tuberculosis (M. Tuberculosis) of which 5&ndash;15% are likely to develop active TB disease during their lifetime.</span><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"> Smear positive PTB cases are more infectious than the smear negative cases(3) .Using the Directly Observed Treatment-Short course (DOTS) program the World Health Organization&rsquo;s global target was to detect 70% of new sputum-smear positive PTB cases.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%"><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Aims<span style="mso-spacerun:yes">&nbsp; </span>and objectives : (1) To study the prevalence of extrapulmonary and sputum positive pulmonary tuberculosis among patients in a tertiary care hospital<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%"><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">(2) To study the various chest roentgenographic patterns in sputum positive tuberculosis patients<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%"><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Materials and methods : A prospective study conducted between 1<sup>st</sup> October 2016 to 28<sup>th</sup>feb 2018, where 100 adult patients<span style="mso-spacerun:yes">&nbsp; </span>with<span style="mso-spacerun:yes">&nbsp; </span>cough of duration of 2 weeks or longer underwent diagnostic evaluation for TB and other pneumonias, including sputum examination and mycobacterial culture, and chest radiograph(CXR). Radiologists reviewed CXRs using a standardised interpretation.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%"><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Results : Of the 100 cases ,78 of them were males and 22 females. 97 were pulmonary tuberculosis and 3 were extrapulmonary tuberculosis. Among 97 pulmonary tuberculosis, 31 were sputum positive remaining negative. The commonest chest radiographic pattern observed is heterogenous opacities suggestive of infiltrates(36.08%), followed by that is cavities(26.8%). Commonest chest radiographic pattern among sputum positive patients is also pulmonary infilterates(58%).among 3 cases of extrapulmonary TB, 2 were neurotuberculosis and 1 was lymph node TB.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%"><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Conclusion :</span><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-fareast-font-family:&quot;Times New Roman&quot;">Tuberculosis remains one of the most deadly infectious diseases and has claimed millions of lives for many years.</span><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">The smear positive PTB case detection rate indicated in this study is significantly lower than the countries which met the 70% target of the World Health Organization. Serial sputum examination showed a considerable rate of positivity in the second sputum sample when compared with the others.radiographic correlation with symptoms still remains a way for starting of antitubercular treatment.<o:p></o:p></span></p>

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Cite This Article:

Bhushan C Shetty, Anoop Shetty, Study of prevalence of extrapulmonary tuberculosis and sputum positive pulmonary tuberculosis with its chest roentgenographic patterns among patients in a tertiary care hospital, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-7 | Issue-8 | August-2018


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