Volume : 7, Issue : 8, August - 2018

ADVERSE EVENTS AMONG PATIENTS OF DRUG RESISTANT TUBERCULOSIS IN INTENSIVE PHASE RECEIVING SECOND LINE ANTI TB TREATMENT

Dr. Rohit Walse, Dr. Mangala Borkar Sonavani

Abstract :

<p>&nbsp;Setting- A DR-TB (Drug Resistant-Tuberculosis) Tertiary Care Center At GMC Aurangabad.</p> <div>Objective: To detect adverse effects of drugs used in drug resistant tuberculosis in intensive phase at the earliest to</div> <div>improve compliance.</div> <div>Design: A cross sectional prospective study.</div> <div>Results: Out of 151 DR TB patients 50.33% patients developed adverse drug events of which gastro intestinal (nausea-21.19%, vomiting-</div> <div>18.54% &amp; 14.56%) manifestations were most common followed by arthralgia (13.90), psychiatric manifestations (insomnia-10.59% &amp;</div> <div>depression-1.32%), injection site swelling/pain (8.6%), impaired hearing (1.32%) and rash (0.66%).</div> <div>Conclusions: Gastrointestinal symptoms are the most common adverse drug events. Taking the pills embedded in banana, pedha or</div> <div>mashed potato along with spacing of drugs and proper guidance helps in reducing gastrointestinal symptoms. Maximum number of</div> <div>adverse events occur in the 􀃶rst 2 months and intensive counseling to patients and caregivers is essential to prevent defaulting.</div>