Volume : 7, Issue : 8, August - 2018

Gestational diabetes mellitus with Dyslipidemia: A case control study among antenatal clinic (ANC) attendees at NSCB Medical College & hospital, Jabalpur, India

Dr Mohammed Asif, Dr Neeraj Pawar

Abstract :

<p class="MsoNormal" style="margin-top:0in;margin-right:-15.3pt;margin-bottom:&#10;8.0pt;margin-left:-14.2pt;text-align:justify;line-height:normal"><b style="mso-bidi-font-weight:normal"><span style="font-size:12.0pt;font-family:&#10;&quot;Times New Roman&quot;,&quot;serif&quot;">Background</span></b><span style="font-size:12.0pt;&#10;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">-. Deranged lipid profile levels may be associated with gestational diabetes mellitus (GDM) and its complications. This study was designed in order to compare the occurrence of dyslipidemia among gestational diabetic and non-diabetic pregnant females.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-top:0in;margin-right:-15.3pt;margin-bottom:&#10;8.0pt;margin-left:-14.2pt;text-align:justify;line-height:normal"><b style="mso-bidi-font-weight:normal"><span style="font-size:12.0pt;font-family:&#10;&quot;Times New Roman&quot;,&quot;serif&quot;">Materials &amp; Methods</span></b><span style="font-size:12.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">-A case control study with the total number of 111 participants, (61 cases and 50 controls) attending ANC clinic of NSCB medical college and hospital, Jabalpur, were recruited.Data on sociodemographic and clinical correlates were collected and Blood glucose and lipid profile estimation was done was done in all participants.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-top:0in;margin-right:-15.3pt;margin-bottom:&#10;8.0pt;margin-left:-14.2pt;text-align:justify;line-height:normal"><b style="mso-bidi-font-weight:normal"><span style="font-size:12.0pt;font-family:&#10;&quot;Times New Roman&quot;,&quot;serif&quot;">Results</span></b><span style="font-size:12.0pt;&#10;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">- Study reveals that 65.6% of cases shows abnormally high level of total cholesterol (&gt;200mg/dl) compare to control group which shows only 4% abnormally high level of total cholesterol. This difference was found statistically significant. Similar trend was observed with LDL and VLDL levels. About 44% of cases show abnormally low level of serum HDL (&lt;35mg/dl) while only 2% of control shows abnormally low level of HDL.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-top:0in;margin-right:-15.3pt;margin-bottom:&#10;8.0pt;margin-left:-14.2pt;text-align:justify;line-height:normal"><b style="mso-bidi-font-weight:normal"><span style="font-size:12.0pt;font-family:&#10;&quot;Times New Roman&quot;,&quot;serif&quot;">Conclusion:</span></b><span style="font-size:12.0pt;&#10;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"> Our results show that lipid profile is significantly deranged in pregnant women with GDM compared to normal pregnant women.<o:p></o:p></span></p>