Volume : 7, Issue : 9, September - 2018

PREVALENCE OF HEPATITIS B INFECTION IN HIV POSITIVE PATIENTS AT A TERTIARY CARE HOSPITAL OF NORTH INDIA

Sumit Kumar, Gian Chand, Ajay Chhabra, Amandeep Singh Sidhu

Abstract :

<p class="MsoNormal" style="text-align:justify;line-height:200%;word-eak:eak-all"><b style="mso-bidi-font-weight:normal"><span style="font-size:14.0pt;line-height:&#10;200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:NanumGothic">Introduction:</span></b><span style="font-size:14.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-fareast-font-family:NanumGothic"> In India hepatitis B virus (HBV) and human immunodeficiency virus (HIV) co-infection is estimated to vary between 2% and 14% in various studies. HIV negatively impacts the disease outcome of hepatitis B and HBV increases hepatic complications in HIV.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%;word-eak:eak-all"><b style="mso-bidi-font-weight:normal"><span style="font-size:14.0pt;line-height:&#10;200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:NanumGothic">Objective</span></b><span style="font-size:14.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-fareast-font-family:NanumGothic">: To study the prevalence of HBsAg positivity in HIV infected patients attending the anti-retroviral therapy center of Guru Nanak Dev Hospital, Amritsar.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%;word-eak:eak-all"><b style="mso-bidi-font-weight:normal"><span style="font-size:14.0pt;line-height:&#10;200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:NanumGothic">Material and methods</span></b><span style="font-size:14.0pt;line-height:200%;&#10;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:NanumGothic">: This retrospective cross-sectional study involved the collection of the results of hepatitis B virus surface antigen (HBsAg)test of all HIV patients who were registered over a period of one year. The data was tabulated and analyzed statistically.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%;word-eak:eak-all"><b style="mso-bidi-font-weight:normal"><span style="font-size:14.0pt;line-height:&#10;200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:NanumGothic">Results</span></b><span style="font-size:14.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-fareast-font-family:NanumGothic">: Of the 435 participants 285 (65.52%) were males and 150 (34.48%) were females, the hepatitis B surface antigen positivity rate was 3.68%. Male in the age group of 19 to 40 years and injection drug users were more susceptible.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%;word-eak:eak-all"><b style="mso-bidi-font-weight:normal"><span style="font-size:14.0pt;line-height:&#10;200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:NanumGothic">Conclusion:</span></b><span style="font-size:14.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-fareast-font-family:NanumGothic">Analyzing this data lead to certain helpful insight that the prevalence of almost 3.68% stresses upon the need for testing for HBsAg in HIV infected patients. For prevention of hepatic complications early treatment should be initiated and those who are negative should be vaccinated.<o:p></o:p></span></p>