Volume : 7, Issue : 9, September - 2018

TO EVALUATE THE ANTI-INFLAMMATORY EFECT OF POLYALTHIA SUBERSOSA PLANT EXTRACT BY USING PROTEIN DENATURATION ASSAY-IN VITRO STUDY

Dr. Selvi. P, Dr. Arul Amutha Elizabeth

Abstract :

<p class="Default" style="text-align:justify">Inflammation is defined as the <span style="mso-spacerun:yes">&nbsp;</span>body response to injury, infection or destruction characterized by heat, redness, pain, swelling and disturbed physiological functions. Inflammation is initiated as a healing process by the tissue in response to an injury by pathogens, irritants or cell damage.Anti-inflammatory drugs like NSAIDS which are more commonly used in practice for various inflammatory conditions have major adverse effects .And hence various <span style="mso-spacerun:yes">&nbsp;</span>plants are believed to be an important source of new chemical substances with potential therapeutic effects and research into plants with alleged folkloric use as anti-inflammatory agents with less side effects should be evaluated for logical research strategy in the search for new anti-inflammatory drugs.</p> <p class="Default" style="text-align:justify">In the current study we evaluated the in vitro anti-inflammatory effect of polyalthiasubersosa plant extract using protein denatuartion assay. The results were the percentage of Inhibition of polyalthiasuberosa plant extract(A1) with product control(A2) and positive control(A0) was 58.64%, 59.65%<span style="mso-spacerun:yes">&nbsp; </span>at concentration sample 100,200&micro;g/ml respectively.</p>