Volume : 7, Issue : 10, October - 2018

A study to predict the response to treatment in paediatric patients treated with anti-epilepsy drug in a tertiary hospital in Central India

Dr. Manoj Bhatnagar, Dr. Samata Warudkar

Abstract :

<p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph;&#10;line-height:200%"><span style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-bidi-font-weight:&#10;bold;mso-bidi-font-style:italic">Objective:</span><span style="font-family:&#10;&quot;Arial&quot;,&quot;sans-serif&quot;">&nbsp;&nbsp;This study was conducted to predict the response to treatment in patients treated with anti-epilepsy drugs.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph;&#10;line-height:200%"><span style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-bidi-font-weight:&#10;bold;mso-bidi-font-style:italic">Methods:&nbsp;This study was an analytical questionnaire-based study conducted in the department of paediatrics in a tertiary hospital in central India from January 2017 to december 2017. Total of 128 patients admitted with epilepsy were studied.< /> Results:&nbsp;Seventy-two patients (56.3%) were boys. The age of the first seizure was under 2 yr old in 90 patients (70.3%). History of feile convulsion, family history of epilepsy and history of asphyxia was found in 16 (12.5%), 41 (32%), and 27 (21.1%) patients, respectively. Seizure etiology was idiopathic in 90 patients (70.3%), and the number of seizures was 1-2 in 36 patients (28.1%). Overall, 57 patients (44.5%) had cereal lesion according to CT scan or MRI, and EEG was abnormal in 101 patients (78.9%).<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph;&#10;line-height:200%"><span style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-bidi-font-weight:&#10;bold;mso-bidi-font-style:italic">Conclusion:&nbsp;Abnormal EEG is an effective factor in treatment response in the children studied.<o:p></o:p></span></p>