Volume : 7, Issue : 11, November - 2018

MINIMUM EFFECTIVE VOLUME OF A COMBINATION OF BUPIVACAINE AND LIGNOCAINE FOR SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK USING ULTRASOUND GUIDED TECHNIQUE

Dr Ramandeep Singh Ahluwalia, Dr Saurabh Khurana

Abstract :

<p>&nbsp;</p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph"><b style="mso-bidi-font-weight:normal"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Background: </span></b><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">To determine the effective volume of a combination of bupivacaine and lignocaine for supraclavicular achial plexus block using ultrasonography (USG).<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph"><b style="mso-bidi-font-weight:normal"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><o:p>&nbsp;</o:p></span></b></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph"><b style="mso-bidi-font-weight:normal"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Methods: </span></b><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:&#10;TimesNewRomanPSMT">This study is an intervention study to determine the minimum effective volume of a drug combination. </span><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">The principle statistical method applied in this study is Staircase Up-down method as described by Dixon and Massey.^{(<a style="mso-endnote-id:edn1" href="file:///C:/Users/WWJ16/Desktop/ADMIN/GJRA/NOV/Word%20Numing%20File/13.Saurabh%20Khurana.docx#_edn1" name="_ednref1" title=""><span class="MsoEndnoteReference"><span style="mso-special-character:footnote"><!--[if !supportFootnotes]--><span class="MsoEndnoteReference"><span style="font-size:12.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-fareast-font-family:&quot;MS Mincho&quot;;mso-fareast-theme-font:minor-fareast;&#10;mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA">[i]</span></span><!--[endif]--></span></span></a>)} <b style="mso-bidi-font-weight:normal"><o:p></o:p></b></span></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph"><b style="mso-bidi-font-weight:normal"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><o:p>&nbsp;</o:p></span></b></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph"><b style="mso-bidi-font-weight:normal"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Results:</span></b><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"> By using the log transformation of the data of required volume and outcome as successful or unsuccessful we have calculated EV 50 = 11ml and EV 90 = 14ml.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><o:p>&nbsp;</o:p></span></p> <p><b style="mso-bidi-font-weight:normal"><span style="font-size:12.0pt;&#10;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:&quot;MS Mincho&quot;;&#10;mso-fareast-theme-font:minor-fareast;mso-ansi-language:EN-US;mso-fareast-language:&#10;EN-US;mso-bidi-language:AR-SA">Conclusion:</span></b><span style="font-size:&#10;12.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;mso-fareast-font-family:&quot;MS Mincho&quot;;&#10;mso-fareast-theme-font:minor-fareast;mso-ansi-language:EN-US;mso-fareast-language:&#10;EN-US;mso-bidi-language:AR-SA"> Minimum Effective Volume in 90% individuals (MEV 90) for a combination of 0.25% bupivacaine and 1% lignocaine for ultrasound guided achial plexus block via supraclavicular approach is 14ml.</span></p> <div style="mso-element:endnote-list"><!--[if !supportEndnotes]-->< clear="all" /> <div style="mso-element:endnote" id="edn1"> <p class="MsoEndnoteText" style="margin-left:.5in;text-align:justify;text-justify:&#10;inter-ideograph;text-indent:-.5in">&nbsp;</p> <p class="MsoEndnoteText" style="margin-left:.5in;text-align:justify;text-justify:&#10;inter-ideograph;text-indent:-.5in"><span style="font-size:10.0pt;font-family:&#10;&quot;Times New Roman&quot;,&quot;serif&quot;"><o:p>&nbsp;</o:p></span></p> </div> </div>