Volume : 7, Issue : 11, November - 2018

To study distribution and antibiotic susceptibility pattern of Escherichia coli from various clinical samples at a tertiary care teaching hospital, in Solapur, Maharashtra

Dr Anu Sharma, Dr Akanksha Shatrughan Bali, Dr N. K. Shaikh

Abstract :

<p>&nbsp;</p> <p class="MsoNormal"><i style="mso-bidi-font-style:normal"><span style="font-size:14.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Escherichia coli (E.coli)</span></i><span style="font-size:14.0pt;line-height:115%;&#10;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"> is one of the leading cause of UTI, and many other infections seen in humans, over the years due to increase rate of antimicrobial resistance among <i style="mso-bidi-font-style:normal">E.coli</i><span style="mso-spacerun:yes">&nbsp; </span>isolates there is growing concern worldwide as it has resulted in limited therapeutic options for treatment. <b style="mso-bidi-font-weight:normal">Aims &amp; objectives</b>- To study distribution and antibiotic susceptibility pattern of <i style="mso-bidi-font-style:&#10;normal">E.coli</i> in various clinical samples. <b style="mso-bidi-font-weight:&#10;normal">Material &amp; method</b>- All samples received in Microbiology department at tertiary care hospital for culture and sensitivity were included in study. Culture positive sample with lactose fermenters were subjected to standard biochemical test for identification and antibiotic susceptibility testing was done along with distribution of <i style="mso-bidi-font-style:normal">E.coli</i><span style="mso-spacerun:yes">&nbsp; </span>in various samples was assessed. <b style="mso-bidi-font-weight:normal">Results</b>- Out of total 2585 samples received for culture &amp; sensitivity, 1142 (44.17%) were culture positive of which 196 (17.16%) were <i style="mso-bidi-font-style:normal">E.coli</i> isolates. Majority of <i style="mso-bidi-font-style:normal">E.coli</i> isolates were from isolated from pus and wound swab 74 (37.75%) followed by urine sample 59 (30.10%) . Antibiotic sensitivity was maximum for imipenem 57%, amikacin 38% and piperacillin tazobactam 35%, nitrofurantoin 24%. Highest resistance was noted for ampicillin 96.5%, quinolones 91.33%, cephalosporins 91.33%<o:p></o:p></span></p>

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To study distribution and antibiotic susceptibility pattern of Escherichia coli from various clinical samples at a tertiary care teaching hospital, in Solapur, Maharashtra , Dr Anu Sharma, Dr Akanksha Shatrughan Bali, Dr N.K. Shaikh , GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-7 | Issue-11 | November-2018


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