Volume : 7, Issue : 11, November - 2018

CLINICOPATHOLOGICAL STUDY OF URINARY BLADDER TUMORS IN A TERTIARY CARE HOSPITAL

Sumalatha Kasturi, Manasa Takkallapelli, Ravinder Thota

Abstract :

<p>&nbsp;</p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">INTRODUCTION:<span style="mso-spacerun:yes">&nbsp; </span></span></b><span lang="EN-IN" style="font-size:&#10;12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Bladder<b style="mso-bidi-font-weight:normal"> </b>tumor is the seventh most common tumor worldwide. As per Indian cancer registry data, it is the 9^th most common cancer accounting for 3.9% of all cancers. <o:p></o:p></span></p> <p class="MsoNormal"><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;&#10;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">The origin of bladder tumor is multifactorial with tobacco smoke as principal cause in most countries. The vast majority of bladder tumors are epithelial in origin. Among these 80-90% are urotheilal carcinomas. <o:p></o:p></span></p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">AIMS &amp; OBJECTIVES: </span></b><span lang="EN-IN" style="font-size:12.0pt;&#10;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">The aim of the present study is to analyse the spectrum of lesions in urinary bladder by histopathological examination of TURBT specimens.<o:p></o:p></span></p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">MATERIALS AND METHODS:</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:&#10;115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"> This is a prospective study conducted at Chalmeda Anand Rao Institute of Medical Sciences in the department of Pathology from August 2017 to July 2018. Clinicopathological data of all the TURBT were analysed.<o:p></o:p></span></p> <p class="MsoNormal"><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;&#10;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="mso-spacerun:yes">&nbsp;</span><b style="mso-bidi-font-weight:normal">RESULTS:</b> A total of 32 cases were studied. The histopathological examination was done and tumors were categorized according to recent 2016 WHO classification. The most common age group was 61-70years (34.3% ) with male to female ratio of 2.5:1. Among the urinary bladder tumors most of them were malignant lesions and most common type of malignancy was non invasive papillary urothelial carcinoma-high grade.<o:p></o:p></span></p> <p class="MsoNormal"><b style="mso-bidi-font-weight:normal"><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">CONCLUSION</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">: Among urinary bladder neoplasms the most common tumor is Non invasive papillary urothelial carcinoma-high grade followed by low grade.</span><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-fareast-font-family:+mn-ea;color:black;mso-font-kerning:12.0pt"> </span><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><o:p></o:p></span></p>