Volume : 4, Issue : 4, April - 2015

Epidural infusion of inj. Bupivacaine hydrochloride 0.125% vs. Bupivacaine hydrochloride 0.125% with fentanyl citrate for post-operative analgesia following abdominal surgery.

Vipul A Patel, Bhumika M Revar

Abstract :

<p>&nbsp;We compared the postoperative epidural analgesia provided by the continuous epidural infusion of Bupivacaine&nbsp;</p> <div>hydrochloride with that provided By a continuous infusion of bupivacaine hydrochloride plus fentanyl citrate.100&nbsp;</div> <div>patients were randomly allocated in 2 groups of n=50 each to receive drugs .Group 1: inj. Bupivacaine hydrochloride&nbsp;</div> <div>0.125% Group 2: inj. Bupivacaine hydrochloride 0.125% and inj. Fentanyl citrate 2mcg/ml. Vitals,Visual analogue score, Sedation score and any&nbsp;</div> <div>side effects were observed. Adding fentanyl citrate 2 mcg/ml to bupivacaine hydrochloride 0.125% significantly reduced pain and increased&nbsp;</div> <div>quality of analgesia.Observation of side effects reflects that o.125% bupivacaine hydrochloride in group 1 has significant propensity to cause&nbsp;</div> <div>nausea and vomiting.Addition of inj. Fentanyl citrate 2mcg/ml to inj. Bupivacaine hydrochloride 0.125%for continuous epidural infusion&nbsp;</div> <div>significantly improved quality of analgesia, provided uniform stable analgesia without an attendant increase in side effects.</div>