Volume : 5, Issue : 3, March - 2016

A Case Report of Testosterone Replacement Therapy in an Adolescent male with Sickle Cell Disease.

Dr. Bhushan Naitam, Dr. Pranay Gandhi

Abstract :

<p>&nbsp;Delayed puberty secondary to hypogonadism is commonly seen in sickle cell disease (SCD), affecting normal growth and development. The condition is rarely treated in SCD for fear of inducing priapism episodes. We present a case report of an Indian adolescent male at 18 years of age who presented with symptoms of delayed puberty as well as frequent stuttering priapism episodes. Endocrinological assessment revealed low serum total testosterone levels. Treatment was commenced monthly with testosterone enanthate which resulted in improved symptoms of delayed puberty, improvement in anthropometric parameters while apparently ameliorating priapism episodes.</p>