Volume : 5, Issue : 4, April - 2016

STUDY ON MORPHOGENESISIS AND HISTOGENESIS OF THE HUMAN FETAL THYMUS IN THE FIRST TRIMESTER.

Zahid Bashir, Sabia Nazir, Javed A. Khan, Shamima Banoo, Yasmin Jan, Showkat Ahmad, M. Arif

Abstract :

<p>&lt;p&gt;&amp;lt;p&amp;gt;&amp;amp;nbsp;The thymus is a remarkable organ with respect to its development and functional differentiation. It is a pinkish grey mass and is a primary lymphoid organ. Thymus develops from third anchial pouch along with inferior parathyroid gland. It increases in mass up to puberty. Afterwards it regresses and remains as a fious mass thereafter. The present study is based on the findings carried out on 10 human fetuses during the first trimester. The fetuses were obtained from various labor rooms, operation theatres and obstetric wards of Government Medical College Jammu. Products of still births and abortions, which were either induced or natural or from hysterotomy procedures were included in the study. On morphological and histological study we observed that the rudiment of the organ was covered by a capsule at stage corresponding to CR length 58 mm. Corticomedullary differentiation occurred at 11 weeks of gestation. From our study we concluded that the developments taking place in human fetal thymus during the first trimester are; capsule formation, lobulation of the organ, differentiation of thymocytes and corticomedullary differentiation.&amp;lt;/p&amp;gt;&lt;/p&gt;</p>