Volume : 5, Issue : 12, December - 2016

ASSOCIATION BETWEEN OBESITY INDICES AND DIABETIC RETINOPATHY

Dr. S. Radhika, Dr. P. Subba Reddy, Dr. K. Nirmala, Dr. S. Ravi, Dr. Christina Mary P. Paul

Abstract :

<p>&nbsp;<b style="text-align: justify;"><u><span lang="EN-IN" style="font-size:14.0pt;&#10;font-family:&quot;Times New Roman&quot;,serif">Aim</span></u></b><u style="text-align: justify;"><span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,serif">:</span></u><span lang="EN-IN" style="text-align: justify; font-size: 14pt; font-family: &quot;Times New Roman&quot;, serif;"> To report the association of generalised and abdominal obesity with</span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;line-height:normal;mso-layout-grid-align:none;text-autospace:none"><span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,serif">Diabetic Retinopathy(DR) in South Indian patients with Type 2 Diabetes . <b><o:p></o:p></b></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;line-height:normal;mso-layout-grid-align:none;text-autospace:none"><u><span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,serif">&nbsp;</span></u></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;line-height:normal;mso-layout-grid-align:none;text-autospace:none"><b><u><span lang="EN-IN" style="font-size:14.0pt;&#10;font-family:&quot;Times New Roman&quot;,serif">Materials and Methods</span></u></b><span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,serif">: Cross sectional study conducted between June 2016 - <o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;line-height:normal;mso-layout-grid-align:none;text-autospace:none"><span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,serif;&#10;mso-bidi-font-weight:bold">November 2016 at ACS medical college&nbsp; . Patient details were entered along <o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;line-height:normal;mso-layout-grid-align:none;text-autospace:none"><span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,serif;&#10;mso-bidi-font-weight:bold">with duration of diabetes, presence or absence of nephropathy and neuropathy &nbsp;. Height , Weight, Waist circumference and Hip circumference were obtained using standard procedures. BMI and Waist Hip ratio(WHR) were calculated using standard formulae. Detailed&nbsp; ophthalmic evaluation of every patient was done . Dilated fundus examination done by a single investigator and retinopathy graded using ICDR </span><span lang="EN-IN" style="font-size:14.0pt;&#10;font-family:&quot;Times New Roman&quot;,serif;mso-fareast-font-family:WarnockPro-Regular">Severity Scale </span><span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,serif;&#10;mso-bidi-font-weight:bold">clinical classification. Statistical analysis was done using SPSS Software.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;line-height:normal;mso-layout-grid-align:none;text-autospace:none"><u><span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,serif;&#10;mso-bidi-font-weight:bold">&nbsp;</span></u></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;line-height:normal;mso-layout-grid-align:none;text-autospace:none"><b><u><span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,serif">Results:</span></u></b><u><span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,serif;&#10;mso-bidi-font-weight:bold"> </span></u><span lang="EN-IN" style="font-size:14.0pt;&#10;font-family:&quot;Times New Roman&quot;,serif;mso-bidi-font-weight:bold">Statistically significant association was noted between Severe DR and Nephropathy (p value &lt; 0.006).<o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;line-height:normal;mso-layout-grid-align:none;text-autospace:none"><u><span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,serif;&#10;mso-bidi-font-weight:bold">&nbsp;</span></u></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;line-height:normal;mso-layout-grid-align:none;text-autospace:none"><u><span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,serif;&#10;mso-bidi-font-weight:bold">&nbsp;<b>Conclusion:</b> </span></u><span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,serif;&#10;mso-bidi-font-weight:bold">Both high BMI and high WHR are associated with presence and severity of DR.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;line-height:normal;mso-layout-grid-align:none;text-autospace:none"><span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,serif;&#10;mso-bidi-font-weight:bold">&nbsp;</span></p>