Volume : 6, Issue : 2, February - 2017
THE STUDY OF OXIDANT & ANTIOXIDANT STATUS IN NEPHROTIC SYNDROME
Dr. Jyoti Dwivedi, Dr. Ravinder Arora, Dr. Purnima D. Sarkar
Abstract :
<p> <span style="text-align: justify; font-size: 12pt; line-height: 150%; font-family: "Times New Roman", serif;">Nephrotic syndrome is a clinical syndrome caused by the increased permeability of the glomerular capillary wall for macromolecules. </span><span style="text-align: justify; font-size: 12pt; line-height: 150%; font-family: "Times New Roman", serif;">Peroxidation of lipid memanes raises the concentration of their by product MDA and the consequent lowering of antioxidants as a result of consumption.</span><span style="text-align: justify; font-size: 12pt; line-height: 150%; font-family: "Times New Roman", serif;"> Therefore, this study was carried out to investigate oxidant and antioxidant status in nephrotic syndrome patients. The blood samples were analyzed for quantitation of malondialdehyde as index of lipid peroxide, total antioxidant capacity, homocysteine and lipoprotein (a). Significantly increased levels of serum lipid peroxide, homocysteine and decreased levels of serum total antioxidant capacity were noticed in the patients with nephrotic syndrome as compared to control subjects. However, significant positive correlation in lipid peroxide with homocysteine and negatively correlated with total antioxidant capacity were observed.</span></p> <p class="MsoNormal" style="text-align:justify;line-height:150%"><span style="font-size:12.0pt; line-height:150%;font-family:"Times New Roman",serif;mso-fareast-font-family: "Times New Roman""><o:p></o:p></span></p>
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Download PDF Journal DOI : 10.15373/2249555XCite This Article:
Dr.Jyoti Dwivedi, Dr.Ravinder Arora, Dr.Purnima D. Sarkar, THE STUDY OF OXIDANT & ANTIOXIDANT STATUS IN NEPHROTIC SYNDROME, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-6, Issue-2, February‾2017