Volume : 6, Issue : 2, February - 2017

Comparison of various hematological indices in patients of ? Thalassemia trait of Jharkhand ,Ranchi, India:A study conducted on 50 patients over 3 years duration

Dr. Sunil Kumar Mahto, Dr. Purnima Bharati, Dr. Arvind Kumar, Dr. Saurav Banerjee, Dr. R. K. Shrivastav

Abstract :

<p>&nbsp;<span style="font-family: &quot;Times New Roman&quot;, serif; font-size: 12pt; text-align: justify;">The two most frequent types of microcytic anemia are beta thalassemia trait (&beta;-TT) and iron deficiency anemia (IDA). We retrospectively evaluated the reliability of various indices for differential diagnosis of microcytosis and</span><span class="apple-converted-space" style="font-family: &quot;Times New Roman&quot;, serif; font-size: 12pt; text-align: justify;">&nbsp;</span><span style="font-family: &quot;Times New Roman&quot;, serif; font-size: 12pt; text-align: justify;">&beta;-TT in the same patient groups.</span><span class="apple-converted-space" style="font-family: &quot;Times New Roman&quot;, serif; font-size: 12pt; text-align: justify;">&nbsp;</span></p> <p class="MsoNormal" style="text-align:justify;line-height:normal"><b><span style="font-size: 12pt; font-family: &quot;Times New Roman&quot;, serif;">Methods</span></b><span style="font-size: 12pt; font-family: &quot;Times New Roman&quot;, serif;">. A total of 50 carefully selected patients with no age restriction were evaluated. We calculated 7 discrimination indices in all patients with hemoglobin (Hb) values of 5.1 to11.6&thinsp;g/dL. The patient groups were evaluated according to red blood cell (RBC) count; red blood distribution width index, Mentzer, Shine and Lal, England and Fraser, Srivastava, Green and King and Ricerca indices<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:normal"><b><span style="font-size: 12pt; font-family: &quot;Times New Roman&quot;, serif;">Results</span></b><span style="font-size: 12pt; font-family: &quot;Times New Roman&quot;, serif;">: Most sensitive index was Shine and Lal, followed by Mentzer index.<o:p></o:p></span></p>