Volume : 6, Issue : 3, March - 2017
STUDY OF SERUM INSULIN LEVEL AND ESTIMATION OF INSULIN RESISTANCE BY HOMA-IR METHOD IN PATIENTS OF BENIGN ESSENTIAL HYPERTENSION
Dr Nupur Srivastava, Dr Pk Khodiar
Abstract :
<p> <span lang="EN-SG" style="text-align: justify; font-family: "Times New Roman", serif; color: rgb(13, 13, 13);">Hyperinsulinemia syndrome describes four conditions—insulin resistance, hyperlipidemia, abdominal obesity, and hypertension—that occur more frequently together than chance alone would dictate. </span><span lang="EN-SG" style="text-align: justify; font-family: "Times New Roman", serif;">Secondary effects from hyperinsulinemia may cause blood pressure elevations; in fact, hyperinsulinemia is strongly correlated with the development of essential hypertension. <span style="color:#0D0D0D;mso-themecolor:text1;mso-themetint:242">Hyperinsulinemia is considered to cause blood pressure elevation and is generally accepted as an independent risk factor for atherosclerosis. It has been revealed previously that insulin-mediated glucose uptake was reduced by 40% in subjects with hypertension. Approximately 50% of hypertensive patients are insulin resistant and these subjects are at great risk of cardiovascular disease. Thus, hypertensive patients with insulin resistance represent a particular disease group and require special medical attention in daily practice.</span></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align: justify;text-justify:inter-ideograph;line-height:150%;layout-grid-mode:char; mso-layout-grid-align:none;text-autospace:none"><span lang="EN-SG" style="font-family:"Times New Roman",serif;mso-fareast-font-family:Batang; color:#0D0D0D;mso-themecolor:text1;mso-themetint:242;mso-fareast-language:KO">Hence this study is aimed to emphasize how common insulin resistance is in patients with essential hypertension and to reemphasize the need to initiate intensive efforts aimed </span><span lang="EN-SG" style="font-family:"Times New Roman",serif; color:#0D0D0D;mso-themecolor:text1;mso-themetint:242">to improve insulin sensitivity </span><span lang="EN-SG" style="font-family:"Times New Roman",serif; mso-fareast-font-family:Batang;color:#0D0D0D;mso-themecolor:text1;mso-themetint: 242;mso-fareast-language:KO">and treating all of the CVD risk factors in patients with essential hypertension, not just the blood pressure.<o:p></o:p></span></p>
Keywords :
Cite This Article:
Dr Nupur Srivastava, Dr PK Khodiar, STUDY OF SERUM INSULIN LEVEL AND ESTIMATION OF INSULIN RESISTANCE BY HOMA-IR METHOD IN PATIENTS OF BENIGN ESSENTIAL HYPERTENSION, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-6, Issue-3, March‾2017