Volume : 6, Issue : 6, June - 2017

Magnetic Resonance Evaluation of Non Vascular and Non Cystic Sellar, Suprasellar and Parasellar lesions

Dr. Abhishek J. Arora, Dr. Richa Arora, Dr. Jyotsna Yarlagadda

Abstract :

<p>&nbsp;<span style="font-family: Arial, sans-serif;">The pituitary gland and parasellar region is a complex crossroad of endocrine, neural, vascular and skeletal structures. Many clinical syndromes are a result of lesions involving the sella turcica and neighboring structures. MRI (Magnetic Resonance Imaging) has replaced CT as the primary imaging study of the sella and parasellar lesions. When used with thin sections, appropriate imaging parameters and contrast enhanced imaging MRI can demonstrate most pituitary adenomas especially small microadenoma and parasellar abnormalities noninvasively without ionizing radiation, exceeding the sensitivity of CT, because of its multiplanar capability, exquisite anatomic detail and characteristic tissue signal intensity.</span></p> <p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif">Aims and Objectives: <o:p></o:p></span></p> <p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l0 level1 lfo1;&#10;tab-stops:list .25in"><!--[if !supportLists]--><span style="font-family:&quot;Arial&quot;,sans-serif;&#10;mso-fareast-font-family:Arial">1)<span style="font-variant-numeric: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp;&nbsp;&nbsp; </span></span><!--[endif]--><span style="font-family:&quot;Arial&quot;,sans-serif">To study the imaging findings of various pathologies involving the sellar, suprasellar and parasellar region.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l0 level1 lfo1;&#10;tab-stops:list 0in .25in"><!--[if !supportLists]--><span style="font-family:&quot;Arial&quot;,sans-serif;&#10;mso-fareast-font-family:Arial">2)<span style="font-variant-numeric: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp;&nbsp;&nbsp; </span></span><!--[endif]--><span style="font-family:&quot;Arial&quot;,sans-serif">To formulate a criteria useful in distinguishing intra sellar lesions with or without supra sellar or para sellar extension, from suprasellar and parasellar tumors.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l0 level1 lfo1;&#10;tab-stops:list 0in .25in"><!--[if !supportLists]--><span style="font-family:&quot;Arial&quot;,sans-serif;&#10;mso-fareast-font-family:Arial">3)<span style="font-variant-numeric: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp;&nbsp;&nbsp; </span></span><!--[endif]--><span style="font-family:&quot;Arial&quot;,sans-serif">To study the diagnostic efficacy of MRI in sellar, suprasellar and parasellar lesions.<o:p></o:p></span></p> <p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif">&nbsp;</span></p> <p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif">Materials and Methods: The study was conducted in our department from June 2014 to July 2016. Total number of cases included in our study were thirty.<o:p></o:p></span></p> <p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif">Selection Criteria: Thiry patients with a clinical suspicion of disorder involving the sellar, suprasellar or parasellar region were evaluated by Magnetic Resonance Imaging of ain during the period of two years. All these patients were followed up to reach therapeutic or histological diagnosis. The symptomatic response of the patients to medical or surgical therapy was noted which helped in the retrospective confirmation of diagnosis. Imaging characteristics of various radiological modalities like X-rays, CT and MRI were recorded in all patients. Management and final diagnosis were also noted. The results were analyzed, studied and compared with similar studies of the past.<o:p></o:p></span></p> <p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif">Exclusion criteria: All the cystic and vascular lesions found in sellar, suprasellar and parasellar location were excluded from the study.<o:p></o:p></span></p> <p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif">The following technique was adapted for the examination:<o:p></o:p></span></p> <p class="MsoNormal"><span style="font-family:&quot;Arial&quot;,sans-serif">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The MRI scans was performed using 1.5T GE MRI scanner using standard head coil for acquisition of images. Axial, coronal and sagittal scans were obtained using multislice multiecho sequences with slice thickness of 2mm. The data acquisition was done using a matrix of 256 x 256. Apart from T1W and T2W images, special sequence like FLAIR and Diffusion Weighted were obtained in required cases with TR/TE of 6000 / 100 msec and 4295 / 112 respectively.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Contrast (Gadolinium-DTPA) at dose of 0.1mmol/kg body weight was given wherever necessary. None of the patients had any adverse reactions following Gadolinium injections.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Sedation was induced in restless patients.<o:p></o:p></span></p>

Keywords :


Cite This Article:

Dr. Abhishek J. Arora, Dr. Richa Arora, Dr. Jyotsna Yarlagadda, Magnetic Resonance Evaluation of Non Vascular and Non Cystic Sellar, Suprasellar and Parasellar lesions, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : VOLUME-6 | ISSUE‾6 | JUNE-2017


Article No. : 1


Number of Downloads : 1


References :