Volume : 6, Issue : 7, July - 2017
A Clinical Study of HbA1c as the Marker of Circulating Lipids in Type 2 Diabetes Patients.
Dr. Jayamohan Kokkat, Dr. Henley Punnen Andrews, Dr. P S Prakash, Dr. Anoop Many, Dr. Bibin P, Dr. Sandheep George Villoth
Abstract :
<p> <b style="text-align: justify;"><span lang="EN-GB">Aims</span></b><span lang="EN-GB" style="text-align: justify;">: The objective of this study was to determine the correlation of HbA1c with circulating lipids in patients with Type 2-diabetes and to find out whether HbA1c can be used as a predictor of circulating Lipids in T2DM. <b>Materials and Methods</b>: The research used a sample of 100 patients who had fulfilled the inclusion criteria and got admitted in a tertiary medical college hospital in south India. HbA1c and FLP tests were done and their relation was analysed.</span></p> <p class="MsoNormal" style="margin-top:3.0pt;text-align:justify;line-height:150%"><b><span lang="EN-GB">Statistical analysis used</span></b><span lang="EN-GB">: </span><span lang="EN-GB">Data analysis was done using a method that is standardized and certified by the NGSP, to determine the correlation between HbA1c and each variable in the FLP. The respective scatter plot was designed with a regression analysis. A follow up study was done after a period of six months to analyze how each variable in FLP was changing with variation in HbA1c. This was done by Spearman’s Rho and Pearson’s correlation test.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-top:3.0pt;text-align:justify;line-height:150%"><b><span lang="EN-GB">Results</span></b><span lang="EN-GB">: The results indicated a positive correlation between HbA1c and S. Cholesterol, LDL and TG. There was a negative correlation between HbA1c & HDL. That is, higher the HbA1c value, lower was the value of HDL. In the follow up study, it was found that increase or decrease of HbA1c was associated with a corresponding increase or decrease in S. Cholesterol, LDL and TG. A Negative correlation of HbA1c with HDL was shown only in the female population in the follow up study. <b>Conclusions</b>: The study concluded that HbA1c could be used as a predictor of Dyslipidemia among the type 2-diabetes patients.<o:p></o:p></span></p>
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Cite This Article:
Dr. Jayamohan Kokkat, Dr. Henley Punnen Andrews, Dr. P S Prakash, Dr. Anoop Many, Dr. Bibin P, Dr. Sandheep George Villoth, A Clinical Study of HbA1c as the Marker of Circulating Lipids in Type 2 Diabetes Patients., GLOBAL JOURNAL FOR RESEARCH ANALYSIS : VOLUME-6 | ISSUE‾7 | JULY -2017