Volume : 6, Issue : 7, July - 2017

Study of serum Magnesium and its association with glycemic control in type II diabetes mellitus

Dr. Prashant Dharme, Dr. Sandip Lambe, Dr. Manisha Achawale

Abstract :

<p>&nbsp;<b style="text-align: justify;"><span lang="EN-IN" style="font-size:12.0pt;&#10;mso-bidi-font-size:11.0pt;font-family:&quot;Times New Roman&quot;,serif">Background:</span></b><span lang="EN-IN" style="text-align: justify; font-size: 12pt; font-family: &quot;Times New Roman&quot;, serif;"> During pre-insulin era diabetes was considered to be endless suffering which was relieved only by death. Diabetes mellitus is a chronic disorder that occurs either when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces. Recently there has been an increasing interest regarding the important role played magnesium in various cell processes in the body.</span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;line-height:normal"><b><span lang="EN-IN" style="font-size:12.0pt;&#10;mso-bidi-font-size:11.0pt;font-family:&quot;Times New Roman&quot;,serif">Objectives:</span></b><span lang="EN-IN" style="font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:&quot;Times New Roman&quot;,serif"> The present study was therefore undertaken to compare the levels of serum Magnesium in diabetic patients and healthy controls and to correlate levels of magnesium with HBA_1C value.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;line-height:normal"><b><span lang="EN-IN" style="font-size:12.0pt;&#10;mso-bidi-font-size:11.0pt;font-family:&quot;Times New Roman&quot;,serif">Material &amp; Methods:</span></b><span lang="EN-IN" style="font-size:12.0pt;mso-bidi-font-size:&#10;11.0pt;font-family:&quot;Times New Roman&quot;,serif"> Serum magnesium levels and HBA_1C values were estimated in 100 type II diabetes mellitus patients and 100 healthy controls. <o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;line-height:normal"><b><span lang="EN-IN" style="font-size:12.0pt;&#10;mso-bidi-font-size:11.0pt;font-family:&quot;Times New Roman&quot;,serif">Results:</span></b><span lang="EN-IN" style="font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:&quot;Times New Roman&quot;,serif"> Mean serum magnesium level was found to be significantly lower in type II diabetes mellitus patients compared to controls. We further observed a significant negative correlation between serum magnesium and HBA_1C value. &nbsp;<o:p></o:p></span></p>