Volume : 6, Issue : 7, July - 2017

A study of Cognitive Impairment among Patients with Chronic Obstructive Pulmonary Disease Compared to Normal Individuals

Dr. Gaurav R. Dubey, Dr. Pranay Gandhi

Abstract :

<p>&nbsp;</p> <h1 style="text-align: justify; line-height: 200%; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;"><span style="font-size:12.0pt;line-height:200%;font-family:&#10;&quot;Arial&quot;,sans-serif;mso-fareast-font-family:&quot;Times New Roman&quot;;font-weight:normal;&#10;mso-bidi-font-weight:bold">The present study was conducted with the aim of evaluating the prevalence of cognitive impairment in patients with COPD in comparison to normal individuals.<o:p></o:p></span></h1> <h1 style="text-align: justify; line-height: 200%; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;"><span style="font-size:12.0pt;line-height:200%;font-family:&#10;&quot;Arial&quot;,sans-serif;mso-fareast-font-family:&quot;Times New Roman&quot;">Materials and Methods:<o:p></o:p></span></h1> <h1 style="text-align: justify; line-height: 200%; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;"><span style="font-size:12.0pt;line-height:200%;font-family:&#10;&quot;Arial&quot;,sans-serif;mso-fareast-font-family:&quot;Times New Roman&quot;;font-weight:normal;&#10;mso-bidi-font-weight:bold">In this case-control study, 87 patients with COPD, whose diagnoses were confirmed by a pulmonologist based on the spirometry test findings, were included. The mini-mental state examination (MMSE) questionnaire was administered for assessing the cognitive impairment.<o:p></o:p></span></h1> <h1 style="text-align: justify; line-height: 200%; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;"><span style="font-size:12.0pt;line-height:200%;font-family:&#10;&quot;Arial&quot;,sans-serif;mso-fareast-font-family:&quot;Times New Roman&quot;">Results:<o:p></o:p></span></h1> <h1 style="text-align: justify; line-height: 200%; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;"><span style="font-size:12.0pt;line-height:200%;font-family:&#10;&quot;Arial&quot;,sans-serif;mso-fareast-font-family:&quot;Times New Roman&quot;;font-weight:normal;&#10;mso-bidi-font-weight:bold">In the case group, 42 patients (48.27%) had no cognitive impairment, 39 (44.82%) had mild, and 6 (6.89%) had moderate cognitive impairment. In the control group, 38 (63.33%) had no cognitive impairment, 20 (33.33%) mild and 2 (3.33 %) moderate cognitive impairment.<o:p></o:p></span></h1> <h1 style="text-align: justify; line-height: 200%; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;"><span style="font-size:12.0pt;line-height:200%;font-family:&#10;&quot;Arial&quot;,sans-serif;mso-fareast-font-family:&quot;Times New Roman&quot;">Conclusion:<o:p></o:p></span></h1> <h1 style="text-align: justify; line-height: 200%; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;"><span style="font-size:12.0pt;line-height:200%;font-family:&#10;&quot;Arial&quot;,sans-serif;mso-fareast-font-family:&quot;Times New Roman&quot;;font-weight:normal;&#10;mso-bidi-font-weight:bold">According the results of the present study, COPD increased the risk of cognitive impairment significantly and is related to the severity of COPD, arterial oxygen saturation, and higher age.</span><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Arial&quot;,sans-serif;&#10;mso-fareast-font-family:&quot;Times New Roman&quot;"><o:p></o:p></span></h1>